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Dr Abhijit Salvekar etc
His start-up
Use our proprietary machine learning algorithms and APIs to predict experiment results and material properties, and manage all your data in one place.
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Bioabsorbable radiopaque water-responsive shape memory embolization plug for temporary vascular occlusion
Patented
References
Polyether F127 Diacrylate (F127DA) |
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Polyether F127 Diacrylate (5-20% wt/vol; subcutaneous; single implant) exhibits in vivo biocompatibility at 2 weeks after subcutaneous implantation in male C57BL/6 mice, with no systemic toxicity or local adverse tissue reactions. It shows slow in vivo biodegradation while maintaining structural presence at the implantation site for at least 2 weeks[1].
Among Polyether F127 Diacrylate (5-20% wt/vol; local coating on root surfaces; single dose), the F127DA-5 hydrogel significantly promotes periodontal ligament regeneration and reduces abnormal healing (root resorption and ankylosis) in a rat model of delayed tooth replantation[1].
The 3D-printed porous scaffold composed of Polyether F127 Diacrylate (15% (w/v); subcutaneous; single implantation) and 3% PEGDA exhibits excellent in vivo biocompatibility, structural stability, and supportive effects on adipose tissue survival after subcutaneous implantation in nude mice, rendering it suitable for breast reconstruction applications[2].
The composite of Polyether F127 Diacrylate (15% (w/v); intra-articular; single injection; in situ photocrosslinking with 405 nm light) and 10% (w/v) GelMA, loaded with 30 μM KGN and 200 ng/mL TGF-β, significantly promotes functional osteochondral regeneration in a rat osteoarthritis model[3].
Among Polyether F127 Diacrylate (5-20% wt/vol; local coating on root surfaces; single dose), the F127DA-5 hydrogel significantly promotes periodontal ligament regeneration and reduces abnormal healing (root resorption and ankylosis) in a rat model of delayed tooth replantation[1].
The 3D-printed porous scaffold composed of Polyether F127 Diacrylate (15% (w/v); subcutaneous; single implantation) and 3% PEGDA exhibits excellent in vivo biocompatibility, structural stability, and supportive effects on adipose tissue survival after subcutaneous implantation in nude mice, rendering it suitable for breast reconstruction applications[2].
The composite of Polyether F127 Diacrylate (15% (w/v); intra-articular; single injection; in situ photocrosslinking with 405 nm light) and 10% (w/v) GelMA, loaded with 30 μM KGN and 200 ng/mL TGF-β, significantly promotes functional osteochondral regeneration in a rat osteoarthritis model[3].
Poly(ethylene glycol) diacrylate (PEGda) |
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General description
Poly(ethylene glycol) diacrylate (PEGDA) is a derivative of polyethylene glycol that can be used for a variety of drug delivery and tissue engineering based applications. It is used as a prepolymer solution that can be used in the formation of a cross-linked polymeric system.
Application
PEGDA can be used in the formation of sulphonated ion exchange membranes for fuel cell applications. It may also be used in the development of novel injectable biodegradable polymers for a variety of biomedical applications.
Poly(ethylene glycol) diacrylate (PEGDA) is a derivative of polyethylene glycol that can be used for a variety of drug delivery and tissue engineering based applications. It is used as a prepolymer solution that can be used in the formation of a cross-linked polymeric system.
Application
PEGDA can be used in the formation of sulphonated ion exchange membranes for fuel cell applications. It may also be used in the development of novel injectable biodegradable polymers for a variety of biomedical applications.
